Supplements to Enhance Stem Cell Output

What we hope to accomplish with supplements is to enhance the output of stem cells from the marrow so that the body has them at its disposal accomplish repair.
This seems simple yet it can sometimes prove to be a daunting task. We are fairly certain that there are certain supplements out there which enhance stem cell output.
What we observe is that most supplements which improve our health seem to do so by a variety of mechanisms.

Certainly many of these supplements work by their antioxidant properties. The body produces free radicals which antioxidants neutralize. When large numbers of free radicals are circulating in the body steps must be taken to neutralize these or damage will occur.
By providing antioxidants a large burden is taken away from the body. The body can better shift it's resources to repair itself. The body repairs itself by the use of stem cells.
All of the cells in your body were not there six years ago. Your body has replaced every cell in your body over the last six years. If we can somehow speed up the bodies output of stem cells we will increase repair and probably slow down aging in the same process.
What we are now finding is that many supplements have multifaceted effects on the body. I have given many lectures all over the world on the effects of supplements on PRP and Stem Cell injections.
I am firmly convinced that supplements do make a difference. They allow the body to repair itself quicker and maintain good health longer.
I have dealt with a number of professional athletes and it is not uncommon to see some of take 50 or more supplement pills per day.

Most of our patients are told to purchase a product called StemX cell. The research on this product is fairly solid in that it comes from the Univ. of South Florida by Drs. Bickford and Sanberg.
These two doctors are very well respected stem cell scientists. They have shown that the components in this supplement seem to dramatically increase stem cell output from the bone marrow.
We recommend that this medication be taken at a dose of 4/day for the first month than 2/day afterwards. The reason that we recommend this is due to its convenience.
We are certainly not opposed if one wishes to take the components of StemX cell individually. With this in mind, I would recommend 4,000-5,000 units of Vitamin D3 per day, Carnosine dosage should be 1500mg a day.
Carnosine is so important in that it appears to help the body produce a compound called Nitric Oxide. It is documented the Nitric Oxide will have a direct effect on the bone marrow causing bone marrow to dramatically increase stem cell production.Green tea dosage should be approximately 500mg, blueberry extract should also be taken on a daily basis.
What is interesting about these supplements is that they probably also slow down aging by stopping the degradation of our telomeres.
The telomeres are found at the end of our DNA strands. Every time the cell reproduces it loses a small snippet of DNA.
When the DNA length reaches a certain critical length the cell is programed to die. By slowing this down we slow down aging and allow our stem cells which will have to undergo a number of cell divisions to weather the DNA damage better. Remember less teleomere damage results in a more effective cell.
We know that Vitamin D, glutathione, astragalus are important in telomere preservation. Remember we want the stem cells to reproduce ( which obviously requires cell division) but we want to maintain their integrity of the DNA.
A simple way of increasing glutathione is by ingesting whey protein. Whey protein comes milk products. It should be considered "superfood". A bit needs to be mentioned about Vitamin D. Vitamin D should be considered a hormone rather than a vitamin. It has far reaching effects throughout the entire body.
There are receptor sites throughout the body in various tissues including brain,prostate,breast pancreas, that have Vitamin D receptors. We know that Vitamin D deficiency seems to make the body more prone to cancer. The research on this is rather conclusive.
Vitamin D also seems to boost our immunity and helps fight off viruses and infections. Although you are getting some vitamin D with StemcellX there is not enough in there to suffice. One should take a total of between 4-5 thousand units per day. Remember to do you math because some other products may also contain Vitamin D.

Another important weapon that we will use is omega-3-fish oil. Omega-3-fish oil is extremely important for our well being. It acts on many different levels. It has potent anti-inflammatory properties and it also seems to have an effect on the teleomeres.
When considering the dosage of Omega-3-fish oil one needs to only be concerned with two components. If you look on the bottle you will see these listed. They are called EPA and DHA.
These two components together need to add up to 3,000mg/day. Also put the fish oil in the freezer and take it directly frozen.
This will eliminate the regurgitation and fishy taste. The fish oil seems to effect the cell membrane in a very positive way. The cell membrane (remember all stem cells contain cell membranes) contains the receptors for growth factors and signaling factors.
Think of the cell membrane as the brain of the cell in addition to acting as the cell's eyes and ears. Unfortunately, due to our poor diets much of our cell membranes are composed of omega-6-fatty acids which effect the integrity of the membrane.
The omega-6-fatty acids are typically the bad hydrogenated fats. These should be avoided. It will typically take the body 4-6 weeks to accomplish an"oil change"in the cell membrane. You will also need to get an assortment of omega -9- fatty acids which are typically found in olive oil and various nuts such as almonds.

Other supplements that we use include those that stabilize mitochondria which are the power houses of the cells and other supplements which increase stem cell output.
It is now felt that many diseases result from the mal -functioning of the mitochondria. This improbably a combination of telomere damage and free radical stress.
Melatonin seems to have a special property of helping to repair some DNA damage in the mitochondria. Another important supplement is Co Q10.
The dosage of Co Q 10 that we recommend is quite large. The CoQ10 will help stabilize the mitochondria of the cells.
Briefly the mitochondria are the powerhouses of the cells. They help produce energy for the cells. When your mitochondria are in trouble you are in trouble.

Another important supplements in the stem cell world includes. Resveratrol. Typical one should take between 250mg and 500/day of Resveratrol.
This seems to turn on certain longevity genes in the body called Sirtuin 1 genes. These genes mimic starvation and exercise. At the present time the only scientifically proven method of extending life is starvation.
This is by and large not practical. For this reason stick with the Resveratrol.

Finally another important supplement to take is Alpha Liopic Acid. Alpha Lipoic Acid helps recharge the various antioxidants that you body utilizes.
It is quite important that you take antioxidants to neutralize the damage done by the bodies' use of oxygen.
The best antioxidants came from phytonutrients of plant and fruit by products. One of the best antioxidants one can take is dark chocolate which is approximately 85% pure (low sugar content). Try to eat at least 5 different colored foods per day.

There are other supplement that we use that will be for another discussion. One of which we have started using is velvet deer antler which stimulates IGF-1 which is the active form of HGH.
This supplement is typically not given to professional athletes since there is a question of it being restricted by their leagues.

No one can say with absolute certainty how important the supplements are but it is fairly well established that these supplements due make a difference in regenerative medicine.
It is unfortunate that many centers that are working with PRP and Stem cells ignore the importance of supplements.